| Registro completo |
| Provedor de dados: |
ArchiMer
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| País: |
France
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| Título: |
Design Polysaccharides of Marine Origin: Chemical Modifications to Reach Advanced Versatile Compounds
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| Autores: |
Chopin, Nathalie
Guillory, Xavier
Weiss, Pierre
Le Bideau, Jean
Colliec-jouault, Sylvia
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| Data: |
2014
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| Ano: |
2014
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| Palavras-chave: |
Alginates
Carrageenans
Chemical modification
Chitin
Chitosan
Grafting
Marine polysaccharide
Polymer
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| Resumo: |
Polysaccharides are among the most abundant macromolecules on Earth. These polymers are easily obtained from various marine resources such as algae, microorganisms and crustacean shells. The structure of these natural carbohydrates is innovative and quite complex. Marine biopolymers represent key scaffolds toward large challenging fields, such as biomedical applications (glycosaminoglycans, regenerative medicine and drug delivery) and tailored biomaterials. Chemical modifications can be applied to modify their final properties in a specific purpose. New functional glycans are achievable and represent a real potential with their intrinsic biocompatibility and biodegradability. Hydroxyl groups are ubiquitous in polysaccharides structure and involved in most of the chemical modifications. The most useful functionalities are ester, ether, amide, amine and alkyl groups. The starting materials could be a natural or depolymerized polymers and the reaction considered with a regioselective point of view. In this review, we will focus on chitin polysaccharide, which is extracted according to industrial processing from exoskeleton of several marine crustaceans. A subsequent deacylation provides chitosan. This marine polysaccharide is very similar to cellulose, a widespread fiber plant organic polymer, except for an amine group on the C2 position instead of a hydroxyl group. Furthermore, seaweeds provide the most abundant sources of polysaccharides: alginates, agar/agarose, carrageenans and fuco dans. In order to improve the original physicochemical and biochemical properties, we will highlight the chemical modifications involving the listed marine polysaccharides of interest.
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| Tipo: |
Text
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| Idioma: |
Inglês
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| Identificador: |
https://archimer.ifremer.fr/doc/00199/31027/29902.pdf
DOI:10.2174/138527281807140515152334
https://archimer.ifremer.fr/doc/00199/31027/
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| Editor: |
Bentham Science Publ Ltd
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| Formato: |
application/pdf
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| Fonte: |
Current Organic Chemistry (1385-2728) (Bentham Science Publ Ltd), 2014 , Vol. 18 , N. 7 , P. 867-895
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| Direitos: |
2014 Bentham Science Publishers. All Rights Reserved.
info:eu-repo/semantics/openAccess
restricted use
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